wholesale Herb Extract What is Perilla Leaf Extract Perilla Leaf Extract is the dried leaf extract of Perilla frutescens (L.) Britt, a plant of Labiatae. It has a variety of health functions and has been widely used in medicine, food, spices, preservatives and other industries. Botanical Source Perilla frutescens (L.) Britt. is an annual herb of Perilla genus in Labiatae. Stems 0.3-2 m high, green or purple, obtuse quadrangular, 4-grooved, densely villous. Leaves broadly ovate or round, 7-13 cm long, 4.5-10 cm wide, apex mucronate or acute, 7-8 pairs of lateral veins, those located at the lower part are slightly close, obliquely ascending; The petiole is 3-5 cm long, with flat back and abdomen, densely villous. Cymes 2-flowered, 1.5-15cm long, densely villous, terminal and axillary racemes biased to one side; Bracts broadly ovoid or suborbicular, about 4 mm long and wide, apex mucronate, covered with reddish brown glandular spots, glabrous, margin membranous; Pedicel 1.5 mm long, densely pilose. Calyx campanulate, 10 veined, about 3 mm long, straight, lower part is villous, with yellow gland spots. Style apex equally 2-lobed. The anterior part of the disk is finger like. Nutlets subglobose, grayish brown, ca. 1.5 mm in diam., reticulate. The flowering period is from August to November, and the fruit period is from August to December. It is distributed in China, Bhutan, India, Indonesia, Japan and North Korea. It is widely cultivated in China. Perilla frutescens has strong adaptability and is not strict with soil requirements. It can grow well on sandy loam, loam and clay with good drainage, and is suitable for soil pH value of 6.0-6.5. It is relatively resistant to high temperature and the suitable temperature for growth is 25 鈩? Perilla frutescens can be used for medicine and spices. The medicinal part is mainly stems, leaves and seeds. The leaves are sweating, antitussive, aromatic stomach strengthening diuretics, which have analgesic, sedative, detoxification effects and can cure colds; Stems have the function of calming qi and calming the fetus; Zi can relieve cough, expectorant, asthma, and relieve depression. Leaves are also used for food and cooked with meat to increase the flavor of the latter. The oil extracted from the seeds is called perilla oil. It is used for food and has antiseptic effect. It is used for industry. Function 1. Sedative and analgesic effects Perillaldehyde and stigmasterol from Perilla frutescens leaf extract have sedative and analgesic activities. Dill celery brain isolated from perilla frutescens can prolong the sleep time induced by cyclohexene barbital in a dose dependent manner. At the dose of less than 10mg/kg, the activity of dill celery brain is almost equal to that of chlorpromazine hydrochloride; In large doses, it can cause hallucination; When the dose reached 718 mg/kg, it was observed that the sleep mice had sustained convulsions. 2. Antipyretic effect Perilla Leaf Extract have slight antipyretic effect on rabbits with experimental fever caused by typhoid mixed vaccine. This may be related to the stimulation of sweat gland secretion. 3. Effect on blood sugar Perilla oil (mainly containing perillaldehyde), the extract of perilla leaf, was orally administered to rabbits 12 hours after fasting, which could dilate the skin blood vessels and increase blood sugar. Oxim made from perilla aldehyde has better effect than perilla oil. 4. Antibacterial and antiviral effects Perillaldehyde and citral, extracts of Perilla frutescens leaves, also have antibacterial effects on pathogenic skin fungi. The volatile oil of Perilla frutescens leaf extract has a strong antibacterial effect on Staphylococcus aureus in gram-positive bacteria and Escherichia coli in gram-negative bacteria, especially Staphylococcus aureus. The extracts of perilla stem and leaf have inhibitory effect on common bacteria. In addition, perillaldehyde, pinene and limonene have anti Pseudomonas aeruginosa activity. 5. Anti allergic effect The antiallergic substances of Perilla frutescens leaves are water-soluble, heat-resistant, and nonvolatile flavor components. They have the ability to directly inhibit the production of TNF by macrophages in vitro. The extract of perilla leaf can also inhibit the production of IgE, DNP IgE antibody and total IgE antibody, but has no effect on DNP IgG antibody. 6. Anti inflammatory effect Perilla leaf juice was injected intraperitoneally into mice, and neutrophils in peritoneal exudate accumulated. After 6 hours of injection, neutrophils accounted for (89 卤 6)% of exudate cells. Furthermore, the effect of perilla leaf juice on tumor necrosis factor (TNF) was observed. It was found that perilla leaf juice could reduce the elevated TNF level in blood by 50%~75%. TNF is mainly a cytokine secreted by macrophages and plays an important role in antibody inflammatory response and immune defense. However, when TNF is excessive, it will cause tissue damage, pathological changes and symptoms, such as fever, anemia, hemorrhage, necrosis, and even shock. Therefore, when excess TNF is inhibited, the above pathological changes and symptoms may be weakened or disappeared. 7. Effect on respiratory system Kechuanbiwenan, which is mainly extracted from perilla leaves, is inhaled through drug gas emission, which has a better antitussive and antiasthmatic effect. The volatile oil of Perilla frutescens leaves has antitussive effect, the antitussive intensity is about 1/5 of that of codeine, and it has certain antagonistic effect on the contraction of isolated guinea pig trachea caused by histamine. 8. Hemostasis Perilla leaf preparation was used to test the coagulation time, thromboplastin time, prothrombin time and euglobulin dissolution time of rabbits after intravenous injection. The results showed that Perilla frutescens could promote the endogenous coagulation system, but had no obvious effect on the exogenous coagulation system. Application 1. Food industry Perilla leaf essential oil is widely used in food industry, such as flavor enhancement, antisepsis, antibacterial, color enhancement, etc. Pigments, aroma components, nutrients, etc. in perilla essential oil can be used to develop and process various foods such as candied fruits, candy, leaf powder, vegetable oil, pastries, and nutritional drinks, or directly process edible perilla leaves, such as pickling, platters, frying, mixing, and whole powder. In addition, rosmarinic acid contained in the essential oil has strong antioxidation and good thermal stability. At present, in Japan and Korea, perilla essential oil is used as a spice for soup, stew and baking. As a new food additive, it will contribute to the R&D and innovation of new products, continuously improve the food quality such as color, flavor and nutrition, optimize the dietary structure of residents, and promote the development of food industry to a certain extent. 2. Pharmaceutical industry Perilla Leaf Extract was orally administered to rabbits 12 hours after fasting, which could dilate the skin blood vessels and increase blood sugar. Oxim made from perilla aldehyde has better effect than perilla oil. can be used in medicine and health food, and has great potential in disease prevention and research and development of health food. Perilla leaf essential oil has good medical and health care effects, and has been used in the treatment of allergy, stroke, myocardial infarction, cerebral infarction, hyperlipidemia, high cholesterol, platelet aggregation and other diseases. As a biological active ingredient, it has been added to the medicine, which has improved the medical quality to a certain extent and significantly improved the therapeutic effect, such as perilla leaf extract, perilla foetus syrup and other products. In addition, it also has health care effects such as anti-aging, protecting vision, enhancing intelligence and memory, and improving sleep. It is a public safe food raw material that has been approved by the US FDA. It is worth mentioning that rosmarinic acid in essential oil is a phenolic acid compound, which has anticoagulant, antibacterial, anti-inflammatory, anti-virus and other activities, and is a multi-functional pharmaceutical intermediate. As a bioactive ingredient, it has many effects and wide applications, providing new raw materials and new ideas for the medical field. 3. Industry Perilla essential oil will become the highlight of industrial development. As a multi-functional, pollution-free and high-quality industrial raw material, it not only plays an important role in household chemicals, such as cosmetics, perfume, aromatherapy, and some high-end luxury care products, but also has outstanding economic benefits and huge development potential in heavy industrial production, such as manufacturing varnish, paint, dyes, machinery oil, light industry textile, leather appliances, etc. About US Manufacturewholesale Herb Extract website:http://www.ciybio.com/herb-extract/